Analytical Sciences


Cover image of volume 37, number 3

Volume 37, Number 3 (2021)

Cover illustration of this month"Graphene-based FRET Aptasensors" by Y. UENO (p.439). See larger image


Highlights − Volume 37, Number 3 (2021)

External-field-induced Assembly for Biological Analytical Chemistry
Shiho TOKONAMI
Keywords: Optical tweezers, photothermal assembly, bioanalysis
Analytical Sciences, 2021, 37(3), 395.
DOI: 10.2116/analsci.highlights2103
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Hot Articles − Volume 37, Number 3 (2021)

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Biomarker Analysis on a Power-free Microfluidic Chip Driven by Degassed Poly(dimethylsiloxane)
Kazuo HOSOKAWA
Keywords: Biomarker, microfluidic chip, microRNA, power-free, degas-driven, point-of-care testing
Analytical Sciences, 2021, 37(3), 399.
DOI: 10.2116/analsci.20SCR04

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Designing Elastic Modulus of Cell Culture Substrate to Regulate YAP and RUNX2 Localization for Controlling Differentiation of Human Mesenchymal Stem Cells
Masashi YAMAZAKI, Satoru KIDOAKI, Hiromichi FUJIE, and Hiromi MIYOSHI
Keywords: Mesenchymal stem cell, styrenated gelatin gel, elastic modulus, mechanotransduction, heterogeneity
Analytical Sciences, 2021, 37(3), 447.
DOI: 10.2116/analsci.20SCP02

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An Open Sandwich Immunochromatography for Non-competitive Detection of Small Antigens
Yoshitaka HARADA, Yuki OHMURO-MATSUYAMA, Mika TSUNA, and Hiroshi UEDA
Keywords: Open sandwich immunoassay, immunochromatography, bone Gla protein, lateral flow assay
Analytical Sciences, 2021, 37(3), 455.
DOI: 10.2116/analsci.20SCP06


Table of Contents − Volume 37, Number 3 (2021)

Highlights

External-field-induced Assembly for Biological Analytical Chemistry
Shiho TOKONAMI
Keywords: Optical tweezers, photothermal assembly, bioanalysis
Analytical Sciences, 2021, 37(3), 395.
DOI: 10.2116/analsci.highlights2103
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Special issue: Analytical Biomaterials

Guest Editorial

“Analytical Biomaterials”
Tamotsu ZAKO, Jun NAKANISHI, Takahito OHSHIRO, and Mizuo MAEDA
Analytical Sciences, 2021, 37(3), 397.
DOI: 10.2116/analsci.GE2103

Reviews

hot article mark
Biomarker Analysis on a Power-free Microfluidic Chip Driven by Degassed Poly(dimethylsiloxane)
Kazuo HOSOKAWA
Keywords: Biomarker, microfluidic chip, microRNA, power-free, degas-driven, point-of-care testing
Analytical Sciences, 2021, 37(3), 399.
DOI: 10.2116/analsci.20SCR04
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Suppressor tRNA-based Biosensors for Detecting Analytes
Atsushi OGAWA
Keywords: Suppressor tRNA, biosensor, cell-free translation, amber suppression, gene regulation
Analytical Sciences, 2021, 37(3), 407.
DOI: 10.2116/analsci.20SCR01
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DNA Base Pair Stacking Assembly of Anisotropic Nanoparticles for Biosensing and Ordered Assembly
Zhiyu HE, Guoqing WANG, Xingguo LIANG, Tohru TAKARADA, and Mizuo MAEDA
Keywords: Anisotropic gold nanoparticles, DNA, base pair stacking, biosensing, assembly
Analytical Sciences, 2021, 37(3), 415.
DOI: 10.2116/analsci.20SCR02
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Strategies for Making Multimeric and Polymeric Bifunctional Protein Conjugates and Their Applications as Bioanalytical Tools
Dani PERMANA, Kosuke MINAMIHATA, Masahiro GOTO, and Noriho KAMIYA
Keywords: Detection probes, bifunctional proteins, site-specific conjugation, polymeric bifunctional proteins, protein polymers
Analytical Sciences, 2021, 37(3), 425.
DOI: 10.2116/analsci.20SCR07
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Graphene-Based FRET Aptasensors
Yuko UENO
Keywords: DNA, aptamer, graphene, sensor, FRET
Analytical Sciences, 2021, 37(3), 439.
DOI: 10.2116/analsci.20SCR08
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Original Papers

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Designing Elastic Modulus of Cell Culture Substrate to Regulate YAP and RUNX2 Localization for Controlling Differentiation of Human Mesenchymal Stem Cells
Masashi YAMAZAKI, Satoru KIDOAKI, Hiromichi FUJIE, and Hiromi MIYOSHI
Keywords: Mesenchymal stem cell, styrenated gelatin gel, elastic modulus, mechanotransduction, heterogeneity
Analytical Sciences, 2021, 37(3), 447.
DOI: 10.2116/analsci.20SCP02
figure

hot article mark
An Open Sandwich Immunochromatography for Non-competitive Detection of Small Antigens
Yoshitaka HARADA, Yuki OHMURO-MATSUYAMA, Mika TSUNA, and Hiroshi UEDA
Keywords: Open sandwich immunoassay, immunochromatography, bone Gla protein, lateral flow assay
Analytical Sciences, 2021, 37(3), 455.
DOI: 10.2116/analsci.20SCP06
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DNA Terminal-Specific Dispersion Behavior of Polystyrene Latex Microparticles Densely Covered with Oligo-DNA Strands Under High-Salt Conditions
Hiroya NAKAUCHI, Mizuo MAEDA, and Naoki KANAYAMA
Keywords: DNA, microparticles, dispersion behavior, terminal-sequence specificity, non-crosslinking aggregation
Analytical Sciences, 2021, 37(3), 461.
DOI: 10.2116/analsci.20SCP04
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Stimuli-responsive Behaviors for Room-temperature Fluorescent Liquid Materials based on N-Heteroacenes and their Mixtures in Response to HCl Vapor and their Facile Synthesis
Kyosuke ISODA, and Yuya ORITA
Keywords: Stimuli-responsive liquid, N-heteroacene, acid sensing, security ink, disorder-order transition
Analytical Sciences, 2021, 37(3), 469.
DOI: 10.2116/analsci.20SCP05
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Using Simple-Structured Split Aptamer for Gold Nanoparticle-based Colorimetric Detection of Estradiol
Chia-Chen CHANG, and Chung-Yu YEH
Keywords: Split aptamer, colorimetric assay, gold nanoparticle, estradiol detection, localized surface plasmon resonance
Analytical Sciences, 2021, 37(3), 479.
DOI: 10.2116/analsci.20SCP07
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Effects of Processing pH on Emission Intensity of Over-1000 nm Near-Infrared Fluorescence of Dye-Loaded Polymer Micelle with Polystyrene Core
Masakazu UMEZAWA, Mae HARUKI, Moe YOSHIDA, Masao KAMIMURA, and Kohei SOGA
Keywords: Near infrared, fluorescence bioimaging, polymer micelle, organic dye, pH
Analytical Sciences, 2021, 37(3), 485.
DOI: 10.2116/analsci.20SCP09
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Analysis of Thickness and Roughness Effects of Artificial Basement Membranes on Endothelial Cell Functions
Jinfeng ZENG and Michiya MATSUSAKI
Keywords: Artificial basement membranes, thickness, endothelial cell function
Analytical Sciences, 2021, 37(3), 491.
DOI: 10.2116/analsci.20SCP10
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A Microfluidic Device for Modulation of Organellar Heterogeneity in Live Single Cells
Ken-Ichi WADA, Kazuo HOSOKAWA, Yoshihiro ITO, and Mizuo MAEDA
Keywords: Microfluidic device, cell fusion, organellar transfer, peroxisome, mitochondria
Analytical Sciences, 2021, 37(3), 499.
DOI: 10.2116/analsci.20SCP11
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Protein-Functionalized Gold Nanoparticles for Antibody Detection Using the Darkfield Microscopic Observation of Nanoparticle Aggregation
Ken YOSHIMURA, PATMAWATI, Mizuo MAEDA, Noriho KAMIYA, and Tamotsu ZAKO
Keywords: Gold nanoparticles, synthesis, aggregation, antibody detection, darkfield microscopy
Analytical Sciences, 2021, 37(3), 507.
DOI: 10.2116/analsci.20SCP12
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Length Discrimination of Homo-oligomeric Nucleic Acids with Single-molecule Measurement
Yuki KOMOTO, Takahito OHSHIRO, and Masateru TANIGUCHI
Keywords: DNA, single-molecule detection, machine learning, polyadenine
Analytical Sciences, 2021, 37(3), 513.
DOI: 10.2116/analsci.20SCP13
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Bio-inert Properties of TEG Modified Dendrimer Interface
Yoshiko MIURA, Yuki KOJIMA, Hirokazu SETO, and Yu HOSHINO
Keywords: Bioinert interface, dendrimer, triethylene glycol, QCM-A
Analytical Sciences, 2021, 37(3), 519.
DOI: 10.2116/analsci.20P388
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Notes

Suppression of Malachite Green-Induced Toxicity to Human Liver Cells Utilizing Host-Guest Chemistry of Cucurbit[7]uril
Riku KUBOTA, Xiaojun LYU, and Tsuyoshi MINAMI
Keywords: Active control, biological effect, host-guest chemistry, cucurbit[7]uril, malachite green
Analytical Sciences, 2021, 37(3), 525.
DOI: 10.2116/analsci.20SCN02
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Effect of a Chloroacetyl Modification on the Suppression of Dissociation of a Fluorescent Molecule from Cells for Antigen-Specific Cell Staining
Ryosuke KANEKO, Masumi KAWAMURA, Akihiro KISHIMURA, Takeshi MORI, and Yoshiki KATAYAMA
Keywords: Antigen, antibody, fluorescence, enzyme, amplification
Analytical Sciences, 2021, 37(3), 529.
DOI: 10.2116/analsci.20SCN03
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Catalytic Amplification of Electrochemical Signal in Homogeneous Solution Using an Entropy-driven DNA Circuit
Yusuke KITAMURA, Keisuke YOSHIMURA, Ryo KURAMOTO, Yousuke KATSUDA, and Toshihiro IHARA
Keywords: Nucleic acids, electrochemical biosensor, inclusion complex, ferrocene, cyclodextrin, homogeneous assay, DNA circuit, signal amplification
Analytical Sciences, 2021, 37(3), 533.
DOI: 10.2116/analsci.20SCN04
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Investigations of Chirality Effects on Undifferentiated State of Mesenchymal Stem Cells Using Soft Nanofibrous Oligopeptide Hydrogels
Toru YOSHITOMI, Hangyu ZHENG, and Keitaro YOSHIMOTO
Keywords: Chirality, 3D culture, mesenchymal stem cell, peptide self-assembly, fibrous hydrogels, cell spreading, undifferentiated state
Analytical Sciences, 2021, 37(3), 539.
DOI: 10.2116/analsci.20SCN05
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Announcements

Analytical Sciences, 2021, 37(3), 545.
DOI: 10.2116/analsci.announce2103