Analytical Sciences


Cover image of volume 31, number 12

Volume 31, Number 12 (2015)

Cover illustration of this month"Fluorescence Probing Live Single-cell Mass Spectrometry for Direct Analysis of Organelle Metabolism" by Tsuyoshi ESAKI and Tsutomu MASUJIMA (p.1211). See larger image


Hot Articles − Volume 31, Number 12 (2015)

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Fluorescence Probing Live Single-cell Mass Spectrometry for Direct Analysis of Organelle Metabolism
Tsuyoshi ESAKI and Tsutomu MASUJIMA
Keywords: Single-cell analysis, live single-cell mass spectrometry, fluorescence imaging, mitochondria, organelle
Analytical Sciences, 2015, 31(12), 1211.
DOI: 10.2116/analsci.31.1211

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Direct Lipido-Metabolomics of Single Floating Cells for Analysis of Circulating Tumor Cells by Live Single-cell Mass Spectrometry
Eiso HIYAMA, Ahmed ALI, Sara AMER, Takanori HARADA, Kazumi SHIMAMOTO, Rie FURUSHIMA, Yasmine ABOULEILA, Samy EMARA, and Tsutomu MASUJIMA
Keywords: Live single-cell mass spectrometry, circulating tumor cell, neuroblastoma, floating cells, lipido-metabolomics, one-drop blood analysis
Analytical Sciences, 2015, 31(12), 1215.
DOI: 10.2116/analsci.31.1215

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Low-cost Methods for Making 3D Fluidic Polymer and Glass Chips Using Metal Templates
Tomohisa YAMASHITA, Kazuyuki YASUKAWA, Tomoko KEMMEI, Yuuko HORII, Eriko NAKAYAMA, Tatsuya MURAMOTO, and Hiroshi TAKADA
Keywords: Fluidic chip, 3D chip, PDMS, glass, epoxy, template
Analytical Sciences, 2015, 31(12), 1261.
DOI: 10.2116/analsci.31.1261


Table of Contents − Volume 31, Number 12 (2015)

Rapid Communications

hot article mark
Fluorescence Probing Live Single-cell Mass Spectrometry for Direct Analysis of Organelle Metabolism
Tsuyoshi ESAKI and Tsutomu MASUJIMA
Keywords: Single-cell analysis, live single-cell mass spectrometry, fluorescence imaging, mitochondria, organelle
Analytical Sciences, 2015, 31(12), 1211.
DOI: 10.2116/analsci.31.1211
figure

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Direct Lipido-Metabolomics of Single Floating Cells for Analysis of Circulating Tumor Cells by Live Single-cell Mass Spectrometry
Eiso HIYAMA, Ahmed ALI, Sara AMER, Takanori HARADA, Kazumi SHIMAMOTO, Rie FURUSHIMA, Yasmine ABOULEILA, Samy EMARA, and Tsutomu MASUJIMA
Keywords: Live single-cell mass spectrometry, circulating tumor cell, neuroblastoma, floating cells, lipido-metabolomics, one-drop blood analysis
Analytical Sciences, 2015, 31(12), 1215.
DOI: 10.2116/analsci.31.1215
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Original Papers

Evaluation of Measurement Precision from Stationary Baseline Noise in Instrumental Analyses
Yuzuru HAYASHI and Nien Fan ZHANG
Keywords: Precision, uncertainty, FUMI theory, ISO 11843, detection limit, stationary process
Analytical Sciences, 2015, 31(12), 1219.
DOI: 10.2116/analsci.31.1219
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Simultaneous Determination of Dopamine, Uric Acid and Guanine at Polyadenine Film Modified Electrode
Hongying LI, Xueliang WANG, and Zhaoxia WANG
Keywords: Adenine, determination, dopamine, guanine, uric acid
Analytical Sciences, 2015, 31(12), 1225.
DOI: 10.2116/analsci.31.1225
figure

Factors to Govern Soluble and Insoluble Aggregate-formation in Monoclonal Antibodies
Jun FUKUDA, Takafumi IWURA, Shigehiro YANAGIHARA, and Kenji KANO
Keywords: Antibody aggregate formation, size-exclusion chromatography, fluorescence spectra with ANS, differential scanning calorimetry, Akaike's information criterion
Analytical Sciences, 2015, 31(12), 1233.
DOI: 10.2116/analsci.31.1233
figure

Electroactive Film of Myoglobin Incorporated in a 3D-porous Calcium Alginate Film with Polyvinyl Alcohol, Glycerin and Gelatin
Xueqin ZHENG, Hong SUN, and Shifeng HOU
Keywords: Myoglobin, porous calcium alginate film, polyvinyl alcohol, glycerol, gelatin, electrochemistry
Analytical Sciences, 2015, 31(12), 1241.
DOI: 10.2116/analsci.31.1241
figure

Trace Analysis of Sinomenine Hydrochloride Using CdTe/CdS Quantum Dots-enhanced Chemiluminescence
Kegang WU and Suqin HAN
Keywords: Chemiluminescence, CdTe/CdS QDs, luminol, sinomenine hydrochloride
Analytical Sciences, 2015, 31(12), 1249.
DOI: 10.2116/analsci.31.1249
figure

Surface Plasmon Resonance Assay of Binding Properties of Antisense Oligonucleotides to Serum Albumins and Lipoproteins
Reina ONISHI, Ayahisa WATANABE, Mado NAKAJIMA, Mitsuaki SEKIGUCHI, Akira KUGIMIYA, Hiroki KINOUCHI, Yoichiro NIHASHI, and Hiroshi KAMIMORI
Keywords: Surface plasmon resonance, serum albumin, lipoprotein, antisense oligonucleotide
Analytical Sciences, 2015, 31(12), 1255.
DOI: 10.2116/analsci.31.1255
figure

hot article mark
Low-cost Methods for Making 3D Fluidic Polymer and Glass Chips Using Metal Templates
Tomohisa YAMASHITA, Kazuyuki YASUKAWA, Tomoko KEMMEI, Yuuko HORII, Eriko NAKAYAMA, Tatsuya MURAMOTO, and Hiroshi TAKADA
Keywords: Fluidic chip, 3D chip, PDMS, glass, epoxy, template
Analytical Sciences, 2015, 31(12), 1261.
DOI: 10.2116/analsci.31.1261
figure

Tube Radial Distribution Chromatography on a Microchip Incorporating Microchannels with a Three-to-One Channel Confluence Point
Naomichi SUZUKI, Kenichi YAMASHITA, Hideaki MAEDA, Masahiko HASHIMOTO, and Kazuhiko TSUKAGOSHI
Keywords: Tube radial distribution phenomenon (TRDP), tube radial distribution chromatography (TRDC), tube radial distribution mixing (TRDM), microchannel
Analytical Sciences, 2015, 31(12), 1267.
DOI: 10.2116/analsci.31.1267
figure

Separation and Purification of ε-Poly-L-lysine with Its Colorimetric Determination Using Dipicrylamine
Hajime KATANO, Yoshihiro KASAHARA, Kazunori USHIMARU, Chitose MARUYAMA, and Yoshimitsu HAMANO
Keywords: Separation, colorimetry, ε-poly-L-lysine, dipicrylamine, high-throughput screening
Analytical Sciences, 2015, 31(12), 1273.
DOI: 10.2116/analsci.31.1273
figure

Ion-responsive Intramolecular Charge-transfer Absorption Using a Pyridinium Benzocrown Ether Conjugate
Tetsuo KUWABARA, Xuanyi TAO, Haocheng GUO, Masayo KATSUMATA, Ikuo UETA, Masaki TAKAHASHI, and Yasutada SUZUKI
Keywords: Chemosensor, ion sensing, intramolecular charge transfer absorption, host-guest chemistry, crown ether, pyridinium
Analytical Sciences, 2015, 31(12), 1279.
DOI: 10.2116/analsci.31.1279
figure

A Selective, Colorimetric and Ratiometric Chemosensor for Hg2+ and Its Application as Test Papers
Hongwei ZHOU, Wei TIAN, Min JIANG, Peng LI, Shihao ZENG, Weixing CHEN, and Aijie MA
Keywords: Chemosensor, coumarin, mercury, ratiometric, colorimetric
Analytical Sciences, 2015, 31(12), 1285.
DOI: 10.2116/analsci.31.1285
figure

Microplate Assay of α-Glucosidase and Its Inhibitors Based on the Direct Reduction of Molybdosilicate by Glucose
Hajime KATANO, Masahiro TAKAKUWA, Takafumi ITOH, and Takao HIBI
Keywords: Microplate assay, α-glucosidase, maltose, glucose, inhibitors, molybdosilicate
Analytical Sciences, 2015, 31(12), 1291.
DOI: 10.2116/analsci.31.1291
figure

In vitro Penetration and in vivo Distribution of Honokiol into the Intervertebral Disc in Rat
Chia-Hsien CHEN, Chang-Jung CHIANG, Lien-Chen WU, Chih-Hong YANG, Yi-Jie KUO, and Tung-Hu TSAI
Keywords: Honokiol, hypoxia inducible factors inhibitor, intervertebral disc, pharmacokinetics, traditional Chinese medicine
Analytical Sciences, 2015, 31(12), 1297.
DOI: 10.2116/analsci.31.1297
figure

Chromium Speciation Using Flow-injection Preconcentration on Xylenol Orange Functionalized Amberlite XAD-16 and Determination in Industrial Water Samples by Flame Atomic Absorption Spectrometry
Reena SAXENA, Niharika SHARMA, and Shelja TIWARI
Keywords: Flow-injection, chromium, speciation, preconcentration, solid phase extraction, flame atomic absorption, spectrometry, Amberlite XAD-16, xylenol orange
Analytical Sciences, 2015, 31(12), 1303.
DOI: 10.2116/analsci.31.1303
figure

Comparison of 265 nm Femtosecond and 213 nm Nanosecond Laser Ablation Inductively Coupled Plasma Mass Spectrometry for Pb Isotope Ratio Measurements
Masaki OHATA, Naoko NONOSE, Ladina DORTA, and Detlef GÜNTHER
Keywords: 265 nm femtosecond laser ablation (fs-LA), 213 nm nanosecond laser ablation (ns-LA), multi-collector inductively coupled plasma mass spectrometry (MC-ICPMS), LA-MC-ICPMS, Pb isotope ratio measurements, solder
Analytical Sciences, 2015, 31(12), 1309.
DOI: 10.2116/analsci.31.1309
figure

Identification of Ancient Silk Using an Enzyme-linked Immunosorbent Assay and Immuno-fluorescence Microscopy
Miaomiao LIU, Jun XIE, Hailing ZHENG, Yang ZHOU, Bing WANG, and Zhiwen HU
Keywords: Ancient silk, identification, ELISA, IFM
Analytical Sciences, 2015, 31(12), 1317.
DOI: 10.2116/analsci.31.1317
figure

Notes

Highly Sensitive Detection of Organophosphorus Pesticides Using 5,10,15,20-Tetrakis(4-hydroxyphenyl)porphyrin
Takaya MURAKAMI, Yoshiaki IWAMURO, Satoshi CHINAKA, Nariaki TAKAYAMA, and Teruyuki KOMATSU
Keywords: 5,10,15,20-Tetrakis(4-hydroxyphenyl)porphyrin, organophosphorus pesticides, UV-visible absorption spectroscopy, solvent dependence, diprotonation
Analytical Sciences, 2015, 31(12), 1325.
DOI: 10.2116/analsci.31.1325
figure

Anchoring Transitions of Liquid Crystals for Optical Amplification of Phospholipid Oxidation Inhibition by Ascorbic Acid
Minmin ZHANG and Chang-Hyun JANG
Keywords: Ascorbic acid, antioxidant, phospholipids, liquid crystals, anchoring transition
Analytical Sciences, 2015, 31(12), 1329.
DOI: 10.2116/analsci.31.1329
figure

Fully Validated Ultra-performance Liquid Chromatography–Tandem Mass Spectrometry Method for the Determination of Fimasartan in Human Plasma
Ji Yeon HYUN, Hyun-Ju KIM, Mi-Ri GWON, Hae Won LEE, Sook Jin SEONG, and Young-Ran YOON
Keywords: Fimasartan, angiotensin II receptor blocker, UPLC-MS/MS, pharmacokinetic study
Analytical Sciences, 2015, 31(12), 1335.
DOI: 10.2116/analsci.31.1335
figure

Mass Spectrometric Quantification of Amphipathic, Polyphenolic Antioxidant of the Pacific Oyster (Crassostrea Gigas)
Hiroaki OKABE, Shu-Ping HUI, Hirotoshi FUDA, Takayuki FURUKAWA, Seiji TAKEDA, Rojeet SHRESTHA, Yusuke MIURA, Mitsugu WATANABE, and Hitoshi CHIBA
Keywords: Amphipathicity, polyphenol, LC-MS/MS, antioxidant, Pacific oyster, polar end-capped ODS
Analytical Sciences, 2015, 31(12), 1341.
DOI: 10.2116/analsci.31.1341
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Announcements

Analytical Sciences, 2015, 31(12), 1345.
DOI: 10.2116/analsci.31.1345