Analytical Sciences

Quantification of Trace Arsenic in Whole Blood by ICP-QMS/QMS

Junko SHIRATAKI, Kazuyuki FUJISAKI, Kouichi SAKAGUCHI, and Nobuyuki SATO

Inorganic Analysis Laboratories, Toray Research Center, Inc., 3-3-7 Sonoyama, Otsu, Shiga 520-8567, Japan

ICP-QMS/QMS was applied to whole blood samples to determine the quantity of trace As. It was found that Fe also causes polyatomic interference with As in conventional ICP-QMS, in addition to Ca and Cl, and ICP-QMS/QMS can remove these interferences in mass-shift mode using O₂ as reaction gas. The ICP-QMS/QMS technique allows the determination of As at sub-ng mL⁻¹ levels.

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