Analytical Sciences

Synthesis of Carbon Dots Originated from Hydroxypropylmethyl Cellulose for Sensing Ciprofloxacin

Shanshan WANG, Yingyi WANG, Kuncheng YANG, Yan ZHONG, Xiaoming YANG, and Zhangbao CHEN

College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China

Hereby, one kind of facile carbon dots (CDs) from hydroxypropylmethyl cellulose (HPMC) has been successfully provided, which obviously emitted blue fluorescence. With the related characterizations in detail, the CDs prepared here mainly consisted of C and O, owing to the functional groups of –OH and C=O on their surfaces. Likewise, the CDs also showed multiple advantages, including excellent photostability, superior dispersity and desirable stability. Moreover, the CDs were applied for sensing ciprofloxacin due to forming complexes with ciprofloxacin, thus leading to the fluorescence quenching of CDs. This proposed method was permitted to sense ciprofloxacin in a linear range of 10 nM L⁻¹ – 90 μM L⁻¹, suggesting that it may broaden the sensing ways for assaying ciprofloxacin.

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