Abstract − Analytical Sciences, 32(12), 1291 (2016).
A Near Infrared Fluorescent Probe for Sensitive Determination of Human Serum Albumin
Xiaodan ZENG,* Mingshuo MA,* Baocun ZHU,** and Lin ZHU***
*Center of Analysis and Measurement, Jilin Institute of Chemical Technology, Jilin 132022, People’s Republic of China
**School of Resources and Environment, University of Jinan, Jinan 250022, People’s Republic of China
***School of Chemical and Pharmaceutical Engineering, Jilin Institute of Chemical Technology, Jilin 132022, People’s Republic of China
**School of Resources and Environment, University of Jinan, Jinan 250022, People’s Republic of China
***School of Chemical and Pharmaceutical Engineering, Jilin Institute of Chemical Technology, Jilin 132022, People’s Republic of China
A fluorescent probe 1 has been successfully developed to determine human serum albumin (HSA). Probe 1 expresses a dramatic fluorescence enhancement to HSA without interference from other amino acids. Under the optimal conditions, the calibration graphs are linear over the range of 0 – 13.3 μg/mL with the limit of determination of 0.61 μg/mL. Thus, this probe shows high sensitivity and selectivity to HSA.
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