Abstract − Analytical Sciences, 21(5), 561 (2005).
Electrochemical Study of Breast Cancer Cells MCF-7 and Its Application in Evaluating the Effect of Diosgenin
Jia LI,* Xuanmin LIU,** Manli GUO,* Yingju LIU,* Shanchao LIU,* and Shouzhuo YAO*
*State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China
**Institute of Life Science and Technology, Hunan University, Changsha 410082, P. R. China
**Institute of Life Science and Technology, Hunan University, Changsha 410082, P. R. China
The electrochemical behavior of breast cancer cells was studied on a graphite electrode by cyclic voltammetry (CV) and potentiometric stripping analysis (PSA). In both cases, only one oxidative peak at approximately +0.75 V was observed. The peak area in PSA was used to study the growth of the cells and the effect of diosgenin on MCF-7 cells. The results showed that diosgenin can effectively inhibit the viability and proliferation of the breast cancer cells.
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