Analytical Sciences

Crystal Structure of 3,3-Dichloro-N-p-methoxyphenyl-4-(2-phenylstryl)-2-azetidinone

Mehmet KABAK,*  Vildan GÜNER,** Yalcçin ELERMAN,* and Tahsin N. DURLU***

*Department of Engineering Physics, Faculty of Engineering, Ankara University,06100, Tandogan, Ankara, Turkey
**Department of Chemistry, Faculty of Sciences, University of Hacettepe, 06532, Beytepe, Ankara, Turkey
***Department of Physics, Faculty of Art and Sciences, University of Kirikkale, 71450, Yahsihan, Kirikkale, Turkey

3,3-Dichloro-N-p-methoxyphenyl-4-(2-phenylstryl)-2-azetidinone (C₂₂H₁₅Cl₂NO₂) was studied by X-Ray analysis, which indicated a monoclinic space group, P2₁/c, with a = 9.619(5), b = 13.879(4), c = 14.161(5)Å, β = 100.16(3)°, V = 1860.8(13)ų, Z = 4, D_c = 1.414 g cm^-3, μ (Mo K_κ) = 0.366 mm^-1 and F₀₀₀ = 816. The structure was solved by direct methods and refined to R = 0.041 for 4026 reflections [I > 2σ(I). The β-lactam ring (2-azetidinone) has antimicrobial affects. The substituents of the methoxyphenyl and phenyl substituents do not change the activity property of the betalactam ring, and the activity properties depend on the planarity of the β-lactam ring.

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