Analytical Sciences

Preparation and Characterization of Alkylphosphonate-Modified Magnesia-Zirconia Composite for Reversed-Phase Liquid Chromatography

Yu-Qi FENG,* Qing-He ZHANG,* Shi-Lu DA,* and Yan ZHANG**

*Department of Chemistry, Wuhan University, Wuhan, 430072, P. R. China
**Laboratory of MRAMP of China, Wuhan, 430072, P. R. China

A new material: magnesia-zirconia composite modified by an alkylphosphonate can be used as a reversed-phasestationary phase for high-performance liquid chromatography. The new material was characterized by elemental analysis,FTIR and ¹³C solid state NMR spectrometry. The pH stability of the new material was investigated using biphenyl and N,N-dimethylaniline as probes with methanol-water (60:40, v/v) as a mobile phase, after the column was continuouslypurged with solutions at extreme pH 2 and pH 11. The chromatographic performance of the new material was studied byusing polycyclic aromatic hydrocarbons (PAHs) and basic compounds as probes. The results indicate that the newmaterial is of high pH stability and can be used for separation of PAHs and basic compounds.

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