Analytical Sciences


Abstract − Analytical Sciences, 16(6), 565 (2000).

Zwitterionic Ion-Exchangers in Liquid Chromatography
Pavel N. NESTERENKO* and Paul R. HADDAD**
*Department of Chemistry, M. V. Lomonosov Moscow State University, 119899, Moscow, Russian Federation
**School of Chemistry, University of Tasmania, GPO Box 252-75, Hobart 7001, Australia
A zwitterionic ion-exchangers represnt a new direction in the development of stationary phases for different modes of high-performance liquid chromatography. The combination of positively and negatively charged sites in a single particle, or within the functional groups of a single molecule attached the surface of an adsorbent, provides unique opportunities to vary the selectivity of the separation. The classification of zwitterionic ion-exchangers based on their structure, distribution of oppositely charged groups, and their applications is considered.