Analytical Sciences

Voltammetric Behavior of Adriamycin and Its Determination at Ni Ion-Implanted Electrode

Jingbo HU and Qilong LI ⁺

Department of Materials and Applied Chemistry, College of Science and Technology, Nihon University, Kanda-Surugadai, Chiyoda, Tokyo 101-8308, Japan

With a Ni ion-implanted glassy carbon electrode (GCE) as the working electrode in 0.1 mol/l HAc-NaAc (pH=4.62) solu-tion, a sensitive reductive wave of adriamycin was obtained by linear-sweep voltammetry. The peak potential was -0.55 V (vs. SCE). The peak current was proportional to the concentration of adriamycin over the range of 5.2«±0 -7 - 1.0«±0 -5 mol/l and the detection limit was 2.7«±0 -7 mol/l. The behavior of the reduction wave was studied and the wave was applied to the determination of adriamycin in urine. The reduction process was quasi-reversible. AES and XPS experi-ments showed that Ni was surely implanted into the surface of the GCE, and the implanted Ni at the GCE improved the electrocatalytic activity. (Keywords: Ni ion implanted glassy carbon electrode, linear sweep voltammetry, electrocatalysis, adriamycin)

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